Tuesday, March 1, 2011

Eye on Health 6.6 Sohu Interview - age-related macular degeneration prevention

 Professor Chen Youxin Sohu Health Channel about age-related macular degeneration prevention
Sohu health: you friends, good afternoon! Welcome to the Sohu interview between healthy.
On June 6 at the National Eye approaching, we Sohu is honored to have a healthy Beijing Union Medical College Hospital, Professor Chen Youxin guest expert interviews, the talk with netizens on the age-related macular degeneration eye disease that terrible.
as the science improves, the more we learn for the eyes and more clear, eye protection and eye diseases are increasingly concerned about the high 70's is our most well-known red eyes, we know the age of 80 cataracts, glaucoma 90 years we have learned, one after another blinding eye disease under control. Now, macular degeneration, eye health has become the main reason affecting the elderly, but the general public awareness of this disease is very limited, on the one hand do not pay attention after the other, I do not know how sick the correct treatment. am very pleased to have invited Professor Chen Youxin between a guest expert interview with netizens talk about prevention and treatment of this disease.
first of Professor Chen with friends to say hello.
Chen Youxin: Honourable friends, good afternoon! very pleased to meet with you friends.
Beijing Union Medical College Hospital Professor Chen Youxin
Sohu health: I simply tell you about Professor Chen Youxin. Professor Chen Youxin as deputy director of Beijing Union Medical College Hospital Department of Ophthalmology, Chinese Medical Association Ophthalmology Branch Secretary of the Chinese Medical Association Ophthalmological Society, vice chairman of the Youth Committee of the Chinese Medical Association Eye Doctor Association member and Director-General. focus on a variety of common and difficult diagnosis and treatment of ocular fundus, such as various retinal vascular diseases such as diabetic retinopathy, central retinal vein occlusion and other laser and surgical treatment of polypoidal choroidal vasculopathy, retinal vascular tumor-like hyperplasia diagnosis and treatment of diseases, age-related macular degeneration photodynamic therapy, intraocular tumor and the diagnosis and treatment of retinal degenerative diseases. photodynamic therapy carried out in recent years as the choroid the treatment of angiogenesis provides a new treatment, and achieved good results.
age-related macular degeneration will be the main cause of blindness
Sohu health: the beginning of interviews, first give us Professor Chen , what is age-related macular degeneration, or age-related macular degeneration is called.
Chen Youxin: Thank Sohu health to provide such a platform, on June 6 at the National Eye draws near, more and more people concerned about the eyes, and I personally think that life outside of visual function is in addition to the second most important function of the human body, if a person lives in darkness, not only their own lives can not take care of themselves, but also troublesome to others, the pain is unimaginable, about 80% of our information is through the visual organ, the eye is obtained, if the information society in the loss of vision, loss is so big.
interview subject today as the ;, the subject is very good, has just introduced the presenters, in the 20th century, before the 80's or 80's, in the case of the Chinese economy is relatively backward, some infectious diseases are more like the past, trachoma, with the social and economic development, has now been well controlled. The second is glaucoma and cataract, particularly cataract, until now, cataract remains the major eye diseases in our country, but the treatment of cataract is developing rapidly these years, we call preventable or curable blindness blind, Why? as long as we go to the hospital, there is capacity to pay, the eye lens can be replaced, they can improve the vision of cataract patients is high.
example, the human body eyes like a camera, and now it can change the lens, but the film, which is now no technical replacement of the retina, such as macular degeneration and other retinal diseases, the retina can not be transplanted, the means of treatment is relatively limited, so age-related macular degeneration has become a major cause of blindness, particularly in Europe and the United States. Although our national age-related macular degeneration is not currently a major cause of blindness, but we should take precautions, prevention is critical, good will from now on attention to this disease.
What is age-related macular degeneration? the name suggests, with the age-related, increase in prevalence with age, increasing year by year, there were reports that people over the age of 50 the prevalence may be a few percent to the age of 60, 70, 80 years old, even to the more than ten per cent, three dozen, so called age-related macular degeneration.
Sohu Health: Can you explain the role of macula in the eye it?
Chen Youxin: the center of a retina of the eye called the macular region, why is it called macular area? because the region which contains a lot of lutein, lutein is yellow, making the region a little yellow color, in particular, In the pathological point of view, so called the macula.
macular center about 500 microns in diameter, the body of the most important part of a visual function. macular degeneration is precisely the center or near the macular region of the degenerative diseases, mainly referring to is bleeding, oozing, edema, scars, etc..
patients with macular degeneration will cause physical and psychological health of the dual pressures of
Sohu: In the event of macular degeneration after which the person will have symptoms? what is the harm?
Chen Youxin: age-related macular degeneration or age-related macular degeneration is called the Western main reason of blindness, so the disease can be blinding, the first symptoms, many patients are visual distortion, and suddenly things do not look straight, look at distorted vision. especially as some elderly people like to read, to see just do not see that word, appears in the middle of the shadow of the visual, the shadow with hemorrhage, edema area relationship, if the area is small, the shadow of the scope of a small, if a large range of bleeding, or edema, scar a large range, and ultimately, blindness, so the damage is very great.
Sohu health: blind since the quality of life will be greatly affected.
Chen Youxin: research in this area in a foreign country is very much lagging behind some of our home, it is mainly because our economy was not as developed countries are now more concerned about the cataract, while the age-related macular degeneration is not too much concern, in fact, the disease impact on quality of life is very large.
first, loss of self-care ability, a lot of elderly people learn to drive, but was more than 60 years of age-related macular degeneration, can not drive, and if children can not help him to more difficult, and even the streets are difficult. at home cooking, and even the label on the bottle condiment see clearly, Kit could not see the word, the morning milk may be poured down on the table, because the want to see to the place just can not see. this regard, we have seen. elderly already osteoporosis, easy to wrestling fractures because not clear, wrestling and fracture more easily.
also psychologically, as we met with some intellectuals, a lifetime reading, now suddenly can not read, a strong psychological sense of loss. It is reported that the elderly macular degeneration macular degeneration than those without the prevalence of depression in the elderly increased significantly.
so we can not understand a lot of young people, the kind of pain after elderly sick, feel, eat drink on the line. this regard, I want to appeal to children and grandchildren or the children do, to understand the parents or grandparents visual health, suffering from macular degeneration if they should be given more help, and even psychological help.
age-related macular degeneration urgent attention
Sohu health: an introduction by Professor Chen, we can understand the age related macular degeneration, or damage caused by a very large, you can not talk about the disease incidence in our country now is how like? is not more easy to get older?
Chen Youxin: In our country, Like diabetes in the sixties and seventies of last century had very little, but now very much, and why? and lifestyle have a certain relationship, and now studies with the diet, eat fewer fruits and vegetables on, coupled with no exercise, obesity, etc. , the incidence rate of high.
age-related macular degeneration is not a disease peculiar to the West, the Chinese people will have, we have a very famous study was done in Guangdong, the early 90s is probably age-related macular degeneration 3% -4%, to 1998 to 8% -9%, equivalent to double, so the problem must be brought to pay attention, the same people with the improvement of living standards among the incidence rates increased, and the large population in China , a small percentage, multiplied by China's 1.3 billion population, is an astronomical figure, so the age-related macular degeneration of the hazards and impact on society must not be ignored.
Sohu health: and as our national social gerontology of the increase, the incidence rate will increase.
Chen Youxin: Of course, our standard of living improves, the level of improved medical care, treatment capacity increase, and now the average life expectancy of the population, our country has entered an aging society, the elderly population increased substantially. coupled with the incidence of macular degeneration is improving, and I believe the number of patients with age-related macular degeneration is increasing year by year.
Sohu health: morbidity and growth rate so high, everyone's perception is still relatively low.
Chen Youxin: I wrote an article published in , Why mention this? as mentioned earlier, the age-related macular degeneration great harm to society in Western countries is the primary cause of blindness in Europe, Australia, the United States, which accounts for medical expenses is fairly large proportion of , alarming figures, it must pay close attention.
more than the population of our country, macular degeneration has gradually increased each year, so we must attach great importance to, and now can cure cataracts, age-related macular degeneration but are difficult to resolve, especially to the in late, so the social awareness must be improved. We have a random survey of 50 people in the clinic, even the eye of the nurse can not tell what is macular degeneration, and its risk factors which can well imagine that our society For ordinary people, age-related macular degeneration, awareness is low, you ask him what is cataract, know, what is glaucoma, know something, know what is macular degeneration? do not know, so we called for urgent improvement To step up publicity efforts.
Sohu health: young people are not sick, is not it relatively small?
Chen Youxin: We are formerly known as age-related macular degeneration, was found to have 50 years of age or 45 years of age will suffer disease, but they are not old, so now it is called age-related macular degeneration, and found that younger age of onset of his trends, like hypertension and myocardial infarction, who have over the past six or seven years old, and now four more than ten years old myocardial infarction, and lifestyle have a certain relationship.
But if a teenager, two-year-old macular hemorrhage occurs, we do not usually referred to as age-related macular degeneration, idiopathic choroidal called foreign neovascularization, we Chinese call central exudative chorioretinopathy (referred to as
Sohu health: but the harm caused is the same.
Chen Youxin: visual impact, or even blindness, this is the same, but also from the treatment point of view, there are also many similarities between
smoking high cholesterol is age-related macular degeneration certainly incentive
Sohu health: disease caused by reasons for the growth now what? what people may have these diseases?
Chen Youxin: just you ask the incidence of age-related macular degeneration causes cause of two points.
the one hand, from 05 onwards, the study of foreign genes and age-related macular degeneration relationship, probably two or three genes found in the relatively positive relationship with macular degeneration, so that if you had macular degeneration, your odds of higher prevalence of family members, especially on the 40 years of age, eyes should check a couple of years, this is a good thing. Secondly, the age-related macular degeneration has a relationship with the race, whites than in yellow, high incidence of some of the black race. There are overseas research, more women than men. the gender, race, heredity, we can not change is inevitable factor.
the other hand, found several important risk factors can be changed. First, smoking, relatively fast paced society today, we sometimes in order to ease the pressure to smoke, but if you smoke, macular degeneration, the probability of illness at least twice the size. A second obesity, high cholesterol, which is more positive. These articles can be controlled by lifestyle changes. There, now advocate a balanced diet, not to say that eating fruits and vegetables all day, but also meat eating species To many, more to be able to ensure intake of various nutrients, in particular, eat more vegetables and fruits, as vegetables, fruits, rich in chlorophyll, zeaxanthin, lycopene, vitamin C, etc., such things have antioxidant function. now there is a theory, age-related macular degeneration is caused by over-oxidation of the macular area of chronic cell injury.
so I do not smoke, balanced diet, eat more fruits and vegetables, not too fat, no high cholesterol, Of course, eye protection should also pay attention all day long at the computer screen, or front of relatively strong light, ten hours sitting down must be bad, so open the computer as a lesson, recess should be rest.
brought photodynamic therapy treatment of macular degeneration in the spring
Sohu health: we've talked about early detection and identification of the problem, then probably we are more concerned about is the present performance of age-related macular changes can not be cured, what treatment do now?
Chen Youxin: In the past there is no good treatment, but did not explore the footsteps of the moment to stop, explore the 80s of last century laser treatment, macular degeneration that would otherwise cause blindness, by laser Vision therapy can be maintained to 0.1 or 0.2 or 0.05, better than the blind. That is what the laser greatest harm? laser is a thermal burns, eyebrows and beard grabbed, the normal tissues and vascular leakage and burned, but only this time kinds of ways.
to 90 years there is a contrast, called indocyanine green angiography, the angiography as a blood vessels nourish the center of the macular area is not, we will cut off the roots, to nourish the blood vessel destruction, extermination, no breeding of blood vessels, neovascularization atrophied. But if the blood vessels nourishing the best in the center of the macular area, damage is relatively large.
to the late 90s, there has been TTT, transpupillary thermotherapy is called, the equivalent of physical therapy, macular laser do not use heat, then increase the temperature slightly, 5 to 10 degrees, inspire some Heat shock protein protection, so that the surrounding normal tissue is protected, and neovascularization gradually destroyed, so they further protect normal tissue, making new blood vessels slowly shrink, eliminate leakage edema, which in turn is a major step forward .
then the 2000, I wrote in 2007 an article called Total rate of photodynamic therapy, which is a milestone, which makes our doctors may exceed the restricted area is a restricted area over the past macula, macular disease in the past that only four words, The mess does not make sense.
now appears photodynamic therapy, can selectively destroy abnormal new blood vessels. abnormal vessels like fake blood, and now we can put this fake After the circulation to the eye, and then use a special laser, this laser does not produce any heat, called cold laser, or called non-thermal laser, when this laser and our neovascularization after the contact interaction of photosensitizer molecules produced photochemical effect, making blood vessels closed, the last generation of vascular thrombosis, some of the methods are more expensive, but there is no way better than good, so we have a way to treatment. We often joke, vision loss is priceless, but no matter how much money, long as they can cure the disease, is always a way, so we are very happy, and now the patients after 2000, in which there has been a lucky misfortune is because of photodynamic therapy.
the safety of photodynamic therapy Note
Sohu sex and health: photodynamic therapy for visual acuity is not affected?
Chen Youxin: photodynamic therapy in our hospital have done 7 years, the biggest advantage is safety, it is estimated now to do in the world more than 200 million, enough to prove its safety, in addition to elimination of abnormal blood vessels, stable vision, we do clinical trials found that, in addition to be able to maintain stable vision for most patients, there are about 30% of patients will improve visual acuity . This method is safe, no toxic side effects, is a good way.
Sohu health: just talked about some of macular degeneration, new blood vessels out, which is what?
Chen Youxin: abnormal blood vessels is a fake shop is harmful to beneficial.
Sohu health: effect of early treatment is better?
Chen Youxin: or repetition of the phrase, see a doctor to take the early, so we must first have awareness of macular degeneration, the elderly can easily too. Second, the periodic inspections. Third, that to treat the disease early.
I just said that the treatment of the development process, both large and medium cities across the country photodynamic therapy for macular degeneration include high myopia caused in permeability caused by various causes, like disease similar to macular degeneration, can be treated through this therapy to really reduce the swelling proved to be stable, to protect our eyesight.
Sohu health: patients need after treatment Note what?
Chen Youxin: photodynamic therapy is that, less than 20 minutes the entire treatment process, treatment should be prepared the day of sunglasses, long-sleeved clothes, the best hats, gloves, because the photosensitizer to light to decomposition, in particular, a large sun in summer, when sunlight to prevent the occurrence of interaction with the photosensitizer, the skin burns. generally faster down the mountain when the sun do better treatment, done after 48 hours to avoid glare.
Sohu Health : no problem lighting up?
Chen Youxin: general home lighting, incandescent or fluorescent lamps are still possible, but I suggest try a little dark, lamp is better, anyway, two days after a 48 hours to recover. < br> choice of treatment must be clear before Sohu health condition
: Speaking of the treatment of diseases, there are a number of breakthroughs and progress, and also made a relatively good effect, for the treatment of macular degeneration, now what are the problems, there is no it? example, we have emphasized disease, standard treatment.
Chen Youxin: I have to say is relatively simple, although we now have new treatments, but there are some differences between different doctor may get different results, why ? most important indications of the master, more professional and sophisticated macular degeneration, we want to know, I have some articles on the website, we can see.
first diagnosis of clear, clear your disease is age-related macular degeneration, or retinopathy, or retinal vascular proliferation, this must be determined before treatment, and try to figure out is late or early, and macular degeneration have the dry and wet points. the so-called dry macular degeneration, is the fundus also No new blood vessels, no bleeding, edema and scar formation, but there are some yellow macular dot calm things. but dry macular degeneration can develop into the wet. the so-called wet macular area is already bleeding, oozing, edema, or scar formation, and took part in the early wet just bleeding, and has been completely scarred, and not, like, so be sure to clear diagnosis before treatment.
Sohu health: So we have to choose hospital, clinic doctors when the need for more attention to some.
Chen Youxin: In any kind of treatment before the disease really want to find out the other, as the patient must also ask, do not blindly treatment because improper treatment may increase the injury. Now network is very developed, such as Sohu search for anything on a search to, what is age-related macular degeneration, I would like is some of the network. Also where can be treated and how treatment should be clear. So before treatment do some homework is good, do not believe one of the words, in some places called a cure macular degeneration is certainly not credible.
Sohu health: you can go to Professor Chen's personal web site have a look. Here we look at the problems some users it.
Professor Chen Youxin questions for on-site users
User: mother has macular degeneration two years ago, when I had a photodynamic therapy, good results, the disease does not develop, I feel very good, there is no second treatments, but the vision began to decline last year, is a decline in the future to do, or how to?
Chen Youxin: This is a very big problem, is a philosophical proposition, because people now have no control over the aging , the age-related macular degeneration is a disease in the aging process, and age-related, so do not have a way to completely cure, the treatment approach we are not a cure or a treatment table, so there may exist a treatment secondary treatment, three treatment, in a foreign country to do three times the average first year, twice a second year, third year to do it again, but the biggest advantage is that the treatment abroad can be covered by medical insurance. so do not expect everything will be fine once the treatment, which is not correct, we must constantly review, because there may be the first treatment.
friends: a few years ago my mother felt a shadow front sway, the check is cataract, but because of macular degeneration, is not it inoperable?
Chen Youxin: macular degeneration, if it is to late, do nothing approach, but still should be the treatment of cataract, and why? as macular degeneration, central vision loss is mainly done after treatment of cataracts may be slightly better peripheral vision, so I do cataract patients the time if I gave him, slightly improved visual acuity is a good thing.
User: My mother had macular degeneration for three years, first the left eye, right eye and macular degeneration are serious this year, a sharp decline in visual acuity, according to Beijing every spring, have opened a Chinese medicine hospital taking little or no effect, I ask you to carry out photodynamic surgery?
Chen Youxin: First the first point, to be confirmed, some basic hospital because of equipment limitations, with little experience, may be misdiagnosed. it is proposed to go to large hospitals is not confirmed macular degeneration, to find out is dry, or wet the; second, macular degeneration does have a tendency to eyes, eyes can be a front and rear, left eye right eye had also entirely possible to be, just could not take Chinese medicine, especially at the less experienced Chinese medicine, or some other method should be adopted.
friends: I am a high degree of myopia, 500 eyes about some of the recent decline in sensory acuity, and sometimes feel the shadows, do not know if there is no serious problem, this is not need to go to hospital?
Chen Youxin: high myopia, we generally considered to be above 600 degrees is called myopia, high myopia of 500 degrees is not known, but 500 degrees is quite high Even four or five people Baidu myopia can sometimes get sick. So if there are shadows in front of the eye fluttering, it may be vitreous opacity, I suggest go to the hospital regularly look up eyes, look around the retina, there is no degeneration area even some patients with cleft, so patients with high myopia, periodic look up eyes.
Professor Chen Youxin recommendations for users their visits time
Moderator: Time is almost up, Professor Chen Youxin conclude our friends some suggestions, tell us about their visits another time.
Chen Youxin: either the patients themselves or relatives of patients or healthy subjects of interest, we must raise awareness of age-related macular degeneration, the disease is more common, so the state must pay close attention, especially at home have relatively large age of the parents, or grandparents aged relatively large, they often want to look up the eyes, hope that early detection, especially over 60 years, the incidence rate may high, it is necessary to raise awareness.
Second, if it is found they have a visual distortion or a front of a shadow, often alternating left and right eye closed, take a look and found that when these symptoms as soon as possible to the relatively large, qualified the hospital for examination, and sometimes not only ophthalmoscopy, but also have the inspection equipment to early detection.
found to be dry if the age-related macular degeneration, our advice is to eat more vegetables, fruits, go out Great to wear dark glasses sun, quit smoking, eat greasy food, maintain proper weight, but also added lutein, which is large-scale tests proved that the United States, if you added lutein, trace elements, vitamins, can a considerable number of people not to late development. for wet macular degeneration in elderly, to go to the hospital to take some formal method of modern technology, formal examination and treatment, such as photodynamic therapy. In addition, you can combine a number of anti-angiogenesis drugs, injection into the vitreous cavity, now more respected combination therapy, so a multi-pronged, often a treatment is not enough, various methods have their own advantages and disadvantages and complement each other, so that the best results .
Here I would like to stress that many elderly people their mobility, only to be filial sons and daughters of the heart, their information is not well-informed, do not know the disease can rule. Today, I tell you, can cure this disease, so Be sure to tell your family, and some people think that age-related macular degeneration can not rule, anyway, have been older, do not read, this is utterly wrong, the elderly but also the quality of life, can not see is very painful, life quality greatly reduced. macular degeneration will be able to treat, as long as the various methods with properly, can keep your vision steady, and this is confidence.
I work at the Beijing Union Medical College Hospital Department of Ophthalmology, every Monday, two, three out of the morning in Beijing Union Medical College Hospital out-patient, we can come to me at this time. In addition we can contact through my personal web page I, www.chenyouxin.haodf.com and chenyouxin010.blog.sohu.com, can leave a message mentioning some problems, as long as I have the time, basically every night, and sometimes even abroad can be answered.
Sohu Health: This concludes today's interview, thank you very much the concern of friends, and Professor Chen Youxin the visit, If you have any specific questions, one can log on Professor Chen Youxin personal website to ask questions, Sohu is also Professor Chen's blog, In addition, you can go look for Professor Chen Beijing Union Medical College Hospital. Thank you!

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